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Mouse Anti-SHC2 Recombinant Antibody (CBXS-2176) (CBMAB-S4939-CQ)

This product is a mouse antibody that recognizes SHC2. The antibody CBXS-2176 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all SHC2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2176
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SHC (Src homology 2 domain containing) transforming protein 2
Entrez Gene ID
25759
UniProt ID
P98077
Alternative Names
SHC Adaptor Protein 2; SHC (Src Homology 2 Domain Containing) Transforming Protein 2; Src Homology 2 Domain-Containing-Transforming Protein C2; Neuronal Shc Adaptor Homolog; SHC-Transforming Protein B; SH2 Domain Protein C2;
Function
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons (By similarity).
Biological Process
Biological Process intracellular signal transductionIEA:InterPro
Biological Process positive regulation of MAPK cascadeIEA:InterPro
Biological Process transmembrane receptor protein tyrosine kinase signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytosol
plasma membrane
PTM
Phosphorylated on tyrosines by the Trk receptors.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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