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Mouse Anti-SLC12A4 Recombinant Antibody (CBXS-4229) (CBMAB-S1481-CQ)

This product is a mouse antibody that recognizes SLC12A4. The antibody CBXS-4229 can be used for immunoassay techniques such as: ELISA, WB.
See all SLC12A4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4229
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 12 (potassium/chloride transporters), member 4
Introduction
This gene encodes a member of the SLC12A transporter family. The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane. This gene is expressed ubiquitously. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Entrez Gene ID
6560
UniProt ID
Q9UP95
Alternative Names
Solute Carrier Family 12 Member 4; Solute Carrier Family 12 (Potassium/Chloride Transporter), Member 4; Electroneutral Potassium-Chloride Cotransporter 1; Erythroid K-Cl Cotransporter 1; HKCC1; KCC1; Solute Carrier Family 12 (Potassium/Chloride Transporters), Member 4; Potassium/Chloride Cotransporter 1; CTC-479C5.17;
Function
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl- exit in NaCl absorbing epithelia (By similarity).
Isoform 4 has no transport activity.
Biological Process
Biological Process ammonium import across plasma membraneISS:ARUK-UCL
Biological Process cell volume homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process chemical synaptic transmissionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process chloride ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process chloride transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process ion transportTAS:Reactome
Biological Process potassium ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process potassium ion import across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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