Sign in or Register   Sign in or Register
  |  

Mouse Anti-SLC20A2 Recombinant Antibody (4B1) (CBMAB-A8181-LY)

The product is antibody recognizes SLC20A2. The antibody 4B1 immunoassay techniques such as: WB, ELISA.
See all SLC20A2 antibodies
Published Data
Fig. 1 Total homogenate from samples of the various regions of the mouse brain including the cerebral cortex, hippocampus, striatum, mid-brain, cerebellum, and spinal cord was applied to the gel and then performed western blotting.
...View More

Summary

Host Animal
Mouse
Specificity
Human
Clone
4B1
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
SLC20A2 (NP_006740.1, 243 a.a. ~ 342 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
solute carrier family 20 (phosphate transporter), member 2
Entrez Gene ID
6575
UniProt ID
Q08357
Alternative Names
GLVR2; Glvr-2; MLVAR; PIT-2
Function
Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not significantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants.
Biological Process
Biological Process ion transportTAS:Reactome
Biological Process phosphate ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Involvement in disease
Basal ganglia calcification, idiopathic, 1 (IBGC1):
A form of basal ganglia calcification, an autosomal dominant condition characterized by symmetric calcification in the basal ganglia and other brain regions. Affected individuals can either be asymptomatic or show a wide spectrum of neuropsychiatric symptoms, including parkinsonism, dystonia, tremor, ataxia, dementia, psychosis, seizures, and chronic headache. Serum levels of calcium, phosphate, alkaline phosphatase and parathyroid hormone are normal. The neuropathological hallmark of the disease is vascular and pericapillary calcification, mainly of calcium phosphate, in the affected brain areas.
Topology
Extracellular: 1-5
Helical: 6-26
Cytoplasmic: 27-46
Helical: 47-67
Extracellular: 68-86
Helical: 87-107
Cytoplasmic: 108-109
Helical: 110-130
Extracellular: 131-142
Helical: 143-163
Cytoplasmic: 164-190
Helical: 191-211
Extracellular: 212-213
Helical: 214-234
Cytoplasmic: 235-482
Helical: 483-503
Extracellular: 504-530
Helical: 531-551
Cytoplasmic: 552-571
Helical: 572-586
Extracellular: 587-593
Helical: 594-609
Cytoplasmic: 610-621
Helical: 622-642
Extracellular: 643-652
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-SLC20A2 Recombinant Antibody (4B1)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare