Rabbit Anti-SLC25A26 Recombinant Antibody (CBXS-1287) (CBMAB-S4146-CQ)

Name: Rabbit Anti-SLC25A26 Recombinant Antibody (CBXS-1287)
SKU: CBMAB-S4146-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

CBXS-1287

Application

Specificity

Mouse, Rat, Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Solute Carrier Family 25 Member 26

Introduction

This gene is a member of the mitochondrial carrier family which includes nuclear-encoded transporters localized on the inner mitochondrial membranes. Members of the family transport important small molecules across the mitochondrial inner membrane. This protein is involved in the transport of S-adenosylmethionine (SAM) into the mitochondria. Mutations in this gene are associated with combined oxidative phosphorylation deficiency 28. Alternative splicing results in multiple transcript variants encoding different isoforms.

Entrez Gene ID

Human	115286
Mouse	67582
Rat	362403

UniProt ID

Human	Q70HW3
Mouse	Q5U680
Rat	D4A6Y6

Alternative Names

Solute Carrier Family 25 Member 26; Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member 26; Solute Carrier Family 25 (S-Adenosylmethionine Carrier), Member 26; Mitochondrial S-Adenosylmethionine Transporter; SAMC; S-Adenosylmethionine Mitochondrial Carrier Protein; COXPD28;

Function

Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Specifically mediates the transport of S-adenosylmethionine (SAM) into the mitochondria.

Biological Process

Biological Process ion transportTAS:Reactome
Biological Process S-adenosyl-L-methionine transportManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Mitochondrion inner membrane

Involvement in disease

Combined oxidative phosphorylation deficiency 28 (COXPD28):
An autosomal recessive mitochondrial disorder characterized by decreased activities of respiratory chain enzymes, and variable clinical manifestations. Clinical features include episodic metabolic decompensation beginning in infancy, mild muscle weakness, cardiorespiratory insufficiency, developmental delay, or even death.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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