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Rabbit Anti-SLC25A26 Recombinant Antibody (CBXS-1287) (CBMAB-S4146-CQ)

This product is a rabbit antibody that recognizes SLC25A26. The antibody CBXS-1287 can be used for immunoassay techniques such as: WB.
See all SLC25A26 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBXS-1287
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Solute Carrier Family 25 Member 26
Introduction
This gene is a member of the mitochondrial carrier family which includes nuclear-encoded transporters localized on the inner mitochondrial membranes. Members of the family transport important small molecules across the mitochondrial inner membrane. This protein is involved in the transport of S-adenosylmethionine (SAM) into the mitochondria. Mutations in this gene are associated with combined oxidative phosphorylation deficiency 28. Alternative splicing results in multiple transcript variants encoding different isoforms.
Entrez Gene ID
Human115286
Mouse67582
Rat362403
UniProt ID
HumanQ70HW3
MouseQ5U680
RatD4A6Y6
Alternative Names
Solute Carrier Family 25 Member 26; Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member 26; Solute Carrier Family 25 (S-Adenosylmethionine Carrier), Member 26; Mitochondrial S-Adenosylmethionine Transporter; SAMC; S-Adenosylmethionine Mitochondrial Carrier Protein; COXPD28;
Function
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Specifically mediates the transport of S-adenosylmethionine (SAM) into the mitochondria.
Biological Process
Biological Process ion transportTAS:Reactome
Biological Process S-adenosyl-L-methionine transportManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Mitochondrion inner membrane
Involvement in disease
Combined oxidative phosphorylation deficiency 28 (COXPD28):
An autosomal recessive mitochondrial disorder characterized by decreased activities of respiratory chain enzymes, and variable clinical manifestations. Clinical features include episodic metabolic decompensation beginning in infancy, mild muscle weakness, cardiorespiratory insufficiency, developmental delay, or even death.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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