Mouse Anti-SLC26A9 Recombinant Antibody (CBXS-3220) (CBMAB-S5961-CQ)

Name: Mouse Anti-SLC26A9 Recombinant Antibody (CBXS-3220)
SKU: CBMAB-S5961-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-3220

Application

ELISA, WB

Immunogen

Partial recombinant corresponding to aa496-606 from human SLC26A9 (NP_443166) with GST tag

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

solute carrier family 26, member 9

Introduction

This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. The product of this gene is a highly selective chloride ion channel regulated by WNK kinases. Alternative splicing results in multiple transcript variants encoding differing isoforms.

Entrez Gene ID

115019

UniProt ID

Q7LBE3

Alternative Names

Solute Carrier Family 26 Member 9; Solute Carrier Family 26 (Anion Exchanger), Member 9; Anion Transporter/Exchanger Protein 9; Solute Carrier Family 26, Member 9; Anion Transporter/Exchanger-9;

Function

DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport (PubMed:11834742).
Mediates chloride/bicarbonate exchange or chloride-independent bicarbonate extrusion thus assuring bicarbonate secretion (PubMed:15800055).
May prefer chloride anions and mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane (By similarity).

Biological Process

Biological Process anion transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process chloride transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process chloride transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process ion transportTAS:Reactome
Biological Process positive regulation of gene expressionManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Cell membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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