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Mouse Anti-SLC26A9 Recombinant Antibody (CBXS-3220) (CBMAB-S5961-CQ)

This product is a mouse antibody that recognizes SLC26A9. The antibody CBXS-3220 can be used for immunoassay techniques such as: ELISA, WB.
See all SLC26A9 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3220
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa496-606 from human SLC26A9 (NP_443166) with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 26, member 9
Introduction
This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. The product of this gene is a highly selective chloride ion channel regulated by WNK kinases. Alternative splicing results in multiple transcript variants encoding differing isoforms.
Entrez Gene ID
115019
UniProt ID
Q7LBE3
Alternative Names
Solute Carrier Family 26 Member 9; Solute Carrier Family 26 (Anion Exchanger), Member 9; Anion Transporter/Exchanger Protein 9; Solute Carrier Family 26, Member 9; Anion Transporter/Exchanger-9;
Function
DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport (PubMed:11834742).
Mediates chloride/bicarbonate exchange or chloride-independent bicarbonate extrusion thus assuring bicarbonate secretion (PubMed:15800055).
May prefer chloride anions and mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane (By similarity).
Biological Process
Biological Process anion transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process chloride transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process chloride transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process ion transportTAS:Reactome
Biological Process positive regulation of gene expressionManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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