Mouse Anti-SLC30A9 Monoclonal Antibody (1C3) (CBMAB-0112-LY)

Name: Mouse Anti-SLC30A9 Monoclonal Antibody (1C3)
SKU: CBMAB-0112-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1C3

Application

IP, MA

Immunogen

Recombinant peptide (Full Length)

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

SLC30A9

Introduction

SLC30A9 is a protein-coding gene. Diseases associated with SLC30A9 include Birk-Landau-Perez Syndrome. Among its related pathways are Metal ion SLC transporters. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and ligand-dependent nuclear receptor transcription coactivator activity. SLC30A9 is ubiquitously expressed with high levels in cerebellum, skeletal muscle, thymus and kidney. SLC30A9 encodes a putative zinc transporter previously associated with Wnt signalling.

Entrez Gene ID

10463

UniProt ID

Q6PML9

Alternative Names

C4orf1; GAC63; HUEL; ZNT9

Function

Acts as a zinc transporter involved in intracellular zinc homeostasis (PubMed:28334855).
Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt-responsive genes (By similarity).

Biological Process

Biological Process cellular zinc ion homeostasisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process nucleotide-excision repairManual Assertion Based On ExperimentTAS:BHF-UCL
Biological Process positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process zinc ion transportManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Membrane
Nucleus
Cytoplasm
Cytoplasmic vesicle
Endoplasmic reticulum
Mainly in the cytoplasm (PubMed:10409434).
Partial co-localization with endoplasmic reticulum (PubMed:28334855).

Involvement in disease

Birk-Landau-Perez syndrome (BILAPES):
An autosomal recessive syndrome characterized by early-childhood onset of different combinations of intellectual disability, muscle weakness, camptocormia, oculomotor apraxia, and nephropathy.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

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Mouse Anti-SLC30A9 Recombinant Antibody (CBXS-0465) (CAT#: CBMAB-S3415-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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