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Mouse Anti-SLC39A13 Recombinant Antibody (2G2) (CBMAB-A8235-LY)

The product is antibody recognizes SLC39A13. The antibody 2G2 immunoassay techniques such as: sELISA, ELISA.
See all SLC39A13 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2G2
Antibody Isotype
IgG1, κ
Application
sELISA, ELISA

Basic Information

Immunogen
SLC39A13 (NP_689477.2, 170 a.a. ~ 226 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
solute carrier family 39 (zinc transporter), member 13
Introduction
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A13 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM
Entrez Gene ID
91252
UniProt ID
Q96H72
Alternative Names
FLJ25785
Function
Acts as a zinc-influx transporter.
Biological Process
Biological Process cellular zinc ion homeostasisManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process connective tissue developmentManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process zinc ion transmembrane transportManual Assertion Based On ExperimentIDA:BHF-UCL
Cellular Location
Golgi apparatus membrane
Involvement in disease
Ehlers-Danlos syndrome, spondylodysplastic type, 3 (EDSSPD3):
A form of Ehlers-Danlos syndrome, a group of connective tissue disorders characterized by skin hyperextensibility, articular hypermobility, and tissue fragility. EDSSPD3 is an autosomal recessive form characterized by a generalized skeletal dysplasia involving mainly the spine and striking clinical abnormalities of the hands, in addition to classic features of Ehlers-Danlos syndrome. Clinical features include postnatal growth retardation, moderate short stature, protuberant eyes with bluish sclerae, hands with finely wrinkled palms, atrophy of the thenar muscles, and tapering fingers. Radiologic features include mild to moderate platyspondyly, mild to moderate osteopenia of the spine, small ileum, flat proximal femoral epiphyses, short, wide femoral necks, and broad metaphyses (elbows, knees, wrists, and interphalangeal joints).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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