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Mouse Anti-SLC43A3 Recombinant Antibody (CBXS-2161) (CBMAB-S4924-CQ)


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Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBXS-2161
Antibody Isotype
IgM
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Specific for an epitope mapping between amino acids 208-226 within an internal region of SLC43A3 isoforms 1 and 2 of mouse origin
Specificity
Mouse, Rat, Human
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Solute Carrier Family 43 Member 3
Entrez Gene ID
Human29015
Mouse58207
Rat311170
UniProt ID
HumanQ8NBI5
MouseA2AVZ9
RatD4A832
Alternative Names
Solute Carrier Family 43 Member 3; Likely Ortholog Of Mouse Embryonic Epithelial Gene 1; Solute Carrier Family 43, Member 3; Protein FOAP-13; FOAP-13; PRO1659; SEEEG-1; EEG1;
Function
Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine (PubMed:26455426, PubMed:32339528).
May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity).
Isoform 1
Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine (PubMed:30910793).
Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane (PubMed:30910793).
Isoform 2
Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine (PubMed:30910793).
Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane (PubMed:30910793).
Biological Process
Hypoxanthine transport
Cellular Location
Basolateral cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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