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Mouse Anti-SLC9A8 Recombinant Antibody (7A11) (CBMAB-N0612-WJ)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
7A11
Antibody Isotype
IgG
Application
WB, IF

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1.2 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Solute Carrier Family 9 Member A8
Introduction
Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral NaCl absorption in epithelia (Xu et al., 2008 [PubMed 18209477]).[supplied by OMIM, Apr 2009]
Entrez Gene ID
Human23315
Mouse77031
Rat311651
UniProt ID
HumanQ9Y2E8
MouseQ8R4D1
RatQ4L208
Alternative Names
Solute Carrier Family 9 Member A8; Solute Carrier Family 9, Subfamily A (NHE8, Cation Proton Antiporter 8), Member 8; Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Member 8; Na(+)/H(+) Exchanger 8; NHE-8; NHE8;
Function
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Biological Process
Biological Process ion transportTAS:Reactome
Biological Process potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of intracellular pHManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Golgi apparatus membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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