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Mouse Anti-SMURF1 Monoclonal Antibody (1A10) (CBMAB-0143-LY)

This product is mouse monoclonal antibody recognizes SMURF1 of human. The antibody 1A10 immunoassay techniques such as: IP, ELISA.
Host Species
Mouse
Application
IP, ELISA
Immunogen
Recombinant peptide (Full Length)
Antibody Isotype
IgG2b
Specificity
Human
Clone
1A10
Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms. E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Promotes ubiquitination and subsequent proteasomal degradation of MAVS.
Alternative Name
KIAA1625
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0143-LY
Conjugates
Size
Price $
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Second antibody and isotype control