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Mouse Anti-SNAPC2 Recombinant Antibody (4B8) (CBMAB-S2854-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
4B8
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa16-115 from human SNAC2 (NP_003074) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
small nuclear RNA activating complex, polypeptide 2, 45kDa
Introduction
This gene encodes a subunit of the snRNA-activating protein complex which is associated with the TATA box-binding protein. The encoded protein is necessary for RNA polymerase II and III dependent small-nuclear RNA gene transcription. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
6618
UniProt ID
Q13487
Alternative Names
Small Nuclear RNA Activating Complex Polypeptide 2; Proximal Sequence Element-Binding Transcription Factor Subunit Delta; Small Nuclear RNA Activating Complex, Polypeptide 2, 45kDa; Small Nuclear RNA Activating Complex, Polypeptide 2, 45kD; SnRNA-Activating Protein Complex 45 KDa Subunit; PSE-Binding Factor Subunit Delta; PTF Subunit Delta; SNAPc Subunit 2;
Function
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Biological Process
Biological Process snRNA transcriptionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process transcription by RNA polymerase IIManual Assertion Based On ExperimentTAS:ProtInc
Biological Process transcription by RNA polymerase IIIManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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