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Rabbit Anti-SNRPF Recombinant Antibody (CBXS-1251) (CBMAB-S4110-CQ)

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Datasheet
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Basic Information

Host Animal
Rabbit
Clone
CBXS-1251
Application
WB, IP, IHC-P, IF
Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Small Nuclear Ribonucleoprotein Polypeptide F
Introduction
SNRPF (Small Nuclear Ribonucleoprotein Polypeptide F) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and Processing of Capped Intronless Pre-mRNA. Gene Ontology (GO) annotations related to this gene include RNA binding. An important paralog of this gene is LSM6.
Entrez Gene ID
Human6636
Mouse69878
Rat680737
UniProt ID
HumanP62306
MouseP62307
RatD4AAT4
Alternative Names
Small Nuclear Ribonucleoprotein Polypeptide F; Sm Protein F; SnRNP-F; Sm-F; SMF; Small Nuclear Ribonucleoprotein F; PBSCF;
Function
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346).
Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346).
Is also a component of the minor U12 spliceosome (PubMed:15146077).
As part of the U7 snRNP it is involved in histone 3'-end processing (PubMed:12975319).
Biological Process
Biological Process 7-methylguanosine cap hypermethylation1 PublicationIC:ComplexPortal
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process RNA splicingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process spliceosomal snRNP assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process U2-type prespliceosome assembly1 PublicationIC:ComplexPortal
Cellular Location
Cytoplasm, cytosol
Nucleus
SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Rabbit Anti-SNRPF Recombinant Antibody (CBXS-1252) (CAT#: CBMAB-S4111-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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