Mouse Anti-SNX13 Recombinant Antibody (CBCNS-001) (CBMAB-R4014-CN)

Name: Mouse Anti-SNX13 Recombinant Antibody (CBCNS-001)
SKU: CBMAB-R4014-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBCNS-001

Application

WB, ICC, IHC-P, IHC-Fr, ELISA

Immunogen

Sorting Nexin 13

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4, 50% Glycerol

Preservative

0.02% Sodium azide

Concentration

0.5 mg/mL

More Infomation

Target

Full Name

Sorting Nexin 13

Introduction

This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008]

Entrez Gene ID

23161

UniProt ID

Q9Y5W8

Alternative Names

Sorting Nexin 13; RGS-PX1; Rgs Domain- And Phox Domain-Containing Protein; RGS Domain- And PHOX Domain-Containing Protein; Sorting Nexin-13; KIAA0713;

Function

May be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis (By similarity).
Acts as a GAP for Galphas.

Biological Process

Biological Process intracellular protein transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of signal transductionIEA:UniProtKB-KW
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Early endosome membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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