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Mouse Anti-SNX15 Recombinant Antibody (CBXS-2740) (CBMAB-S5491-CQ)

This product is a mouse antibody that recognizes SNX15. The antibody CBXS-2740 can be used for immunoassay techniques such as: ELISA, WB.
See all SNX15 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2740
Antibody Isotype
IgG3, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa51-140 from human SNX15 (NP_037438) with GST tag
Specificity
Human
Antibody Isotype
IgG3, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
sorting nexin 15
Introduction
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.
Entrez Gene ID
29907
UniProt ID
Q9NRS6
Alternative Names
Sorting Nexin 15; Clone Iota Unknown Protein; Sorting Nexin-15; HSAF001435;
Function
May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN.
Biological Process
Intracellular protein transport
Cellular Location
Cytoplasm
Membrane
Cytoplasmic vesicle membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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