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Mouse Anti-SNX20 Recombinant Antibody (CBXS-5051) (CBMAB-S2272-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-5051
Antibody Isotype
IgG2a, κ
Application
ELISA, ICC, IF

Basic Information

Immunogen
SNX20 (NP_699168.1, 47 a.a.-128 a.a) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Sorting Nexin 20
Introduction
SNX20 interacts with the cytoplasmic domain of PSGL1 (SELPLG; MIM 600738) and cycles PSGL1 into endosomes.
Entrez Gene ID
124460
UniProt ID
Q7Z614
Alternative Names
Sorting Nexin 20; Selectin Ligand-Interactor Cytoplasmic 1; SLIC1; Selectin Ligand Interactor Cytoplasmic 1; Sorting Nexin-20; SLIC-1;
Function
May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion.
Biological Process
Protein transport
Cellular Location
Early endosome membrane
Cell membrane
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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