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Mouse Anti-SPANXB1 Recombinant Antibody (CBXS-2889) (CBMAB-S5638-CQ)

This product is a mouse antibody that recognizes SPANXB1. The antibody CBXS-2889 can be used for immunoassay techniques such as: ELISA, WB.
See all SPANXB1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2889
Antibody Isotype
IgM, κ
Application
ELISA, WB

Basic Information

Immunogen
Full length recombinant protein corresponding to aa1-103 of human SPANXB1 (AAH34472) with GST tag
Specificity
Human
Antibody Isotype
IgM, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SPANX Family Member B1
Introduction
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular family member contains an additional 18 nucleotides in its coding region compared to the other family members in the same gene cluster. This family member is also subject to gene copy number variation. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis.
Entrez Gene ID
728695
UniProt ID
Q9NS25
Alternative Names
SPANX Family Member B1; Cancer/Testis Antigen Family 11, Member 2; Nuclear-Associated Protein SPAN-Xb; Cancer/Testis Antigen 11.2; SPANX Family, Member B2; SPANX Family, Member F2; SPANX Family Member F1; SPANXB2; SPANXF1; SPANX-B; CT11.2;
Biological Process
Spermatid development
Cellular Location
Cytoplasm
Nucleus
Associated with nuclear craters.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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