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Mouse Anti-SPATA33 Recombinant Antibody (CBWJC-4452) (CBMAB-C5842WJ)

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJC-4452
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Spermatogenesis Associated 33
Introduction
SPATA33 (Spermatogenesis Associated 33) is a Protein Coding gene.
Entrez Gene ID
UniProt ID
Alternative Names
Spermatogenesis Associated 33; C16orf55; Spermatogenesis-Associated Protein 33; Chromosome 16 Open Reading Frame 55;
Function
Plays an important role in sperm motility and male fertility (By similarity).
Required for sperm midpiece flexibility and for the localization of sperm calcineurin to the mitochondria (By similarity).
Promotes mitophagy as well as acts as an autophagy mediator in male germline cells (By similarity).
Links damaged mitochondria to autophagosomes via its binding to the outer mitochondrial membrane protein VDAC2, as well as to key autophagy machinery component ATG16L1 (By similarity).
Biological Process
Mitophagy
Cellular Location
Cytoplasm, cytosol
Nucleus
Cytoplasm
Mitochondrion
More Infomation
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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