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Mouse Anti-SPN Recombinant Antibody (W3/13) (CBMAB-C12451-LY)

The product is antibody recognizes SPN. The antibody W3/13 immunoassay techniques such as: FC.
Host Species
Mouse
Application
FC
Immunogen
Rat thymocyte membrane glycoproteins
Antibody Isotype
IgG1
Specificity
Rat
Clone
W3/13
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-C12451-LY
Conjugates
Size
Price $
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Second antibody and isotype control