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Mouse Anti-SRL Recombinant Antibody (XIIC4) (CBMAB-0855CQ)

This product is a mouse antibody that recognizes SRL. The antibody XIIC4 can be used for immunoassay techniques such as: IF, IHC-Fr, Inhib, IP, WB.
See all SRL antibodies
Published Data
Fig. 1 Expression of SAR and SERCA2 protein in aging mouse cardiac muscle.
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Fig. 2 Abnormal SR structures in skeletal muscle from SAR-deficient mice.
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Summary

Host Animal
Mouse
Specificity
Rabbit, Mouse, Guinea pig, Dog, Human
Clone
XIIC4
Antibody Isotype
IgG1
Application
IF, IHC-Fr, Inhib, IP, WB

Basic Information

Immunogen
Full length native protein (purified) from Rabbit Sarcalumenin
Specificity
Rabbit, Mouse, Guinea pig, Dog, Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Sarcalumenin
Introduction
Sarcalumenin is a calcium-binding protein that can be found in the sarcoplasmic reticulum of striated muscle. May be involved in the regulation of calcium transport.
Entrez Gene ID
Human6345
Mouse106393
Rabbit501099
Guinea pig100719273
Dog490030
UniProt ID
HumanQ86TD4
MouseQ7TQ48
RabbitP13666
Guinea pigH0VLW5
DogA0A8C0RBZ6
Alternative Names
SRL; sarcalumenin
Biological Process
Biological Process endocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process endosomal transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Sarcoplasmic reticulum lumen
Sarcoplasmic reticulum membrane
May associate with the sarcoplasmic reticulum membrane, via a calcium-dependent mechanism.
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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