Mouse Anti-SRPX2 Recombinant Antibody (CBXS-4342) (CBMAB-S1587-CQ)

Name: Mouse Anti-SRPX2 Recombinant Antibody (CBXS-4342)
SKU: CBMAB-S1587-CQ
Rating: 5 (1 reviews)

See all SRPX2 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-4342

Application

ELISA, WB, IHC, IF

Specificity

Human, Mouse, Pig

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Sushi Repeat Containing Protein, X-Linked 2

Introduction

This gene encodes a secreted protein that contains three sushi repeat motifs. The encoded protein may play a role in the development of speech and language centers in the brain. This protein may also be involved in angiogenesis. Mutations in this gene are the cause of bilateral perisylvian polymicrogyria, rolandic epilepsy, speech dyspraxia and cognitive disability.

Entrez Gene ID

Human	27286
Mouse	68792
Pig	100153130

UniProt ID

Human	O60687
Mouse	Q8R054
Pig	F1S1M3

Alternative Names

Sushi Repeat Containing Protein, X-Linked 2; Sushi-Repeat Protein Upregulated In Leukemia; SRPUL; Sushi-Repeat Protein Up-Regulated In Leukemia; Sushi-Repeat-Containing Protein, X-Linked 2; Sushi Repeat-Containing Protein SRPX2;

Function

Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development.

Biological Process

Biological Process angiogenesisIEA:UniProtKB-KW
Biological Process cell motilityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cell-cell adhesionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of cell migration involved in sprouting angiogenesisISS:UniProtKB
Biological Process positive regulation of synapse assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process vocalization behaviorIEA:Ensembl

Cellular Location

Secreted
Cytoplasm
Cell surface
Synapse

Involvement in disease

Rolandic epilepsy, impaired intellectual development, and speech dyspraxia, X-linked (RESDX):
A condition characterized by the association of rolandic seizures with oral and speech dyspraxia, and intellectual disability. Rolandic seizures occur during a period of significant brain maturation. During this time, dysfunction of neural network activities such as focal discharges may be associated with specific developmental disabilities resulting in specific cognitive impairments of language, visuo-spatial abilities or attention.

PTM

Contains chondroitin sulfate chains.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-SRPX2 Recombinant Antibody (CBXS-4342)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry