Sign in or Register   Sign in or Register
  |  

Mouse Anti-SSH2 Recombinant Antibody (CBXS-0732) (CBMAB-S3663-CQ)

This product is a mouse antibody that recognizes SSH2. The antibody CBXS-0732 can be used for immunoassay techniques such as: S-ELISA, ELISA.
See all SSH2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-0732
Antibody Isotype
IgG2a, κ
Application
S-ELISA, ELISA

Basic Information

Immunogen
SSH2 (NP_203747, 20 a.a.-117 a.a) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
slingshot homolog 2 (Drosophila)
Introduction
This gene encodes a protein tyrosine phosphatase that plays a key role in the regulation of actin filaments. The encoded protein dephosphorylates and activates cofilin, which promotes actin filament depolymerization. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
85464
UniProt ID
Q76I76
Alternative Names
Slingshot Protein Phosphatase 2; SSH-Like Protein 2; SSH-2L; Protein Phosphatase Slingshot Homolog 2; Slingshot Homolog 2 (Drosophila); EC 3.1.3.16;
Function
Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
Biological Process
Biological Process actin cytoskeleton organizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of actin filament polymerizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein dephosphorylationManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytoplasm, cytoskeleton
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-SSH2 Recombinant Antibody (CBXS-0732)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare