Mouse Anti-SSTR1 Recombinant Antibody (CBXS-3217) (CBMAB-S5958-CQ)

Name: Mouse Anti-SSTR1 Recombinant Antibody (CBXS-3217)
SKU: CBMAB-S5958-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-3217

Application

ELISA

Immunogen

SSTR1 (AAH35618, 1aa-60aa) partial recombinant protein with GST tag

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

somatostatin receptor 1

Introduction

Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28.

Entrez Gene ID

6751

UniProt ID

P30872

Alternative Names

Somatostatin Receptor 1; SRIF-2; SS-1-R; SS1-R; SS1R; Somatostatin Receptor Type 1;

Function

Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na+/H+ exchanger via pertussis toxin insensitive G proteins.

Biological Process

Biological Process cellular response to estradiol stimulusManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cellular response to leukemia inhibitory factorIEA:Ensembl
Biological Process cerebellum developmentIEA:Ensembl
Biological Process forebrain developmentIEA:Ensembl
Biological Process G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerManual Assertion Based On ExperimentTAS:ProtInc
Biological Process glutamate receptor signaling pathwayIEA:Ensembl
Biological Process negative regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process neuropeptide signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to starvationIEA:Ensembl
Biological Process spermatogenesisIEA:Ensembl

Cellular Location

Cell membrane

Topology

Extracellular: 1-56
Helical: 57-84
Cytoplasmic: 85-94
Helical: 95-120
Extracellular: 121-131
Helical: 132-153
Cytoplasmic: 154-175
Helical: 176-196
Extracellular: 197-219
Helical: 220-244
Cytoplasmic: 245-270
Helical: 271-296
Extracellular: 297-303
Helical: 304-327
Cytoplasmic: 328-391

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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