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Mouse Anti-SSU72 Recombinant Antibody (CBXS-3603) (CBMAB-S0889-CQ)

This product is a mouse antibody that recognizes SSU72. The antibody CBXS-3603 can be used for immunoassay techniques such as: WB.
See all SSU72 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3603
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Recombinant full length human SSU72(NP_054907)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SSU72 Homolog, RNA Polymerase II CTD Phosphatase
Introduction
SSU72 (SSU72 Homolog, RNA Polymerase II CTD Phosphatase) is a Protein Coding gene. Among its related pathways are Chromatin Regulation / Acetylation and mRNA surveillance pathway. Gene Ontology (GO) annotations related to this gene include phosphoprotein phosphatase activity and CTD phosphatase activity. An important paralog of this gene is SSU72P3.
Entrez Gene ID
29101
UniProt ID
Q9NP77
Alternative Names
SSU72 Homolog, RNA Polymerase II CTD Phosphatase; CTD Phosphatase SSU72; EC 3.1.3.16; SSU72 RNA Polymerase II CTD Phosphatase Homolog (S. Cerevisiae); RNA Polymerase II Subunit A C-Terminal Domain Phosphatase SSU72; Ssu72 RNA Polymerase II CTD Phosphatase Homolog (Yeast); PNAS-120; HSPC182;
Function
Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK.
Biological Process
Biological Process dephosphorylation of RNA polymerase II C-terminal domainManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process mRNA polyadenylationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process termination of RNA polymerase II transcriptionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
Cytoplasm
Predominantly in the cytosol.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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