SSU72

SSU72 (SSU72 Homolog, RNA Polymerase II CTD Phosphatase) is a Protein Coding gene. Among its related pathways are Chromatin Regulation / Acetylation and mRNA surveillance pathway. Gene Ontology (GO) annotations related to this gene include phosphoprotein phosphatase activity and CTD phosphatase activity. An important paralog of this gene is SSU72P3.

Full Name

SSU72 Homolog, RNA Polymerase II CTD Phosphatase

Function

Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK.

Biological Process

Biological Process dephosphorylation of RNA polymerase II C-terminal domainManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process mRNA polyadenylationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process termination of RNA polymerase II transcriptionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus
Cytoplasm
Predominantly in the cytosol.

Anti-SSU72 antibodies

Mouse Anti-SSU72 Recombinant Antibody (CBXS-3603) (CBMAB-S0889-CQ)

Datasheet

SDS

Target: SSU72

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-3603

Application*: WB

Mouse Anti-SSU72 Recombinant Antibody (CBXS-4149) (CBMAB-S1402-CQ)

Datasheet

SDS

Target: SSU72

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-4149

Application*: WB

Mouse Anti-SSU72 Recombinant Antibody (CBXS-4533) (CBMAB-S1773-CQ)

Datasheet

SDS

Target: SSU72

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4533

Application*: WB, IH

Rabbit Anti-SSU72 Recombinant Antibody (CBXS-5383) (CBMAB-S2596-CQ)

Datasheet

SDS

Target: SSU72

Host: Rabbit

Specificity: Human, Mouse, Rat, Monkey, Hamster, Chicken, Cattle, Dog, Pig, Guinea pig

Clone: CBXS-5383

Application*: WB, IP

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)