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Mouse Anti-SSX4 Recombinant Antibody (CBXS-3062) (CBMAB-S5808-CQ)

This product is a mouse antibody that recognizes SSX4. The antibody CBXS-3062 can be used for immunoassay techniques such as: ELISA, IF, WB.
See all SSX4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3062
Antibody Isotype
IgG2a, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa91-189 from human SSX4 (NP_005627) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
synovial sarcoma, X breakpoint 4
Introduction
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
Entrez Gene ID
6759
UniProt ID
O60224
Alternative Names
SSX Family Member 4; Synovial Sarcoma, X Breakpoint 4; Cancer/Testis Antigen 5.4; CT5.4; Protein SSX4; SSX4 SSX4B; SSX4A;
Function
Could act as a modulator of transcription.
Biological Process
Regulation of DNA-templated transcription
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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