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Mouse Anti-STAP2 Recombinant Antibody (CBXS-2276) (CBMAB-S5038-CQ)

This product is a mouse antibody that recognizes STAP2. The antibody CBXS-2276 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all STAP2 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse
Clone
CBXS-2276
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
signal transducing adaptor family member 2
Introduction
This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
106766
UniProt ID
Q8R0L1
Alternative Names
AW049765; STAP-2
Function
Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.
Cellular Location
Cytoplasm
PTM
Phosphorylated on tyrosine. Tyr-250 may be important for interaction with kinases. Phosphorylated by PTK6 at Tyr-250 modulates PTK6-mediated STAT3 activation. Tyr-22 and Tyr-322 appears to be phosphorylated by SRC.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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