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Mouse Anti-STAT3 Monoclonal Antibody (2F12) (CBMAB-0200-LY)

This product is mouse monoclonal antibody recognizes STAT3 of human. The antibody 2F12 immunoassay techniques such as: MA, WB.
Host Species
Mouse
Application
MA, WB
Immunogen
Recombinant peptide (Full Length)
Antibody Isotype
IgG2a
Specificity
Human
Clone
2F12
Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
Alternative Name
APRF
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0200-LY
Conjugates
Size
Price $
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Second antibody and isotype control