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Mouse Anti-STC1 Recombinant Antibody (CBXS-3806) (CBMAB-S1077-CQ)

This product is a mouse antibody that recognizes STC1. The antibody CBXS-3806 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all STC1 antibodies
Published Data
Fig.1 Western blotting analysis of the expression of STC-1 in BGC after stable transfection.
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Fig,2 Immunohistochemical staining of STC-1 in tumor tissues of nude mice.
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Summary

Host Animal
Mouse
Specificity
Mouse, Human
Clone
CBXS-3806
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
stanniocalcin 1
Introduction
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
Entrez Gene ID
Human6781
Mouse20855
UniProt ID
HumanP52823
MouseO55183
Alternative Names
STC
Function
Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia.
Biological Process
Biological Process bone developmentManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular calcium ion homeostasisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to cAMPIEA:Ensembl
Biological Process cellular response to glucocorticoid stimulusIEA:Ensembl
Biological Process cellular response to hypoxiaIEA:Ensembl
Biological Process chondrocyte proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process decidualizationIEA:Ensembl
Biological Process embryo implantationIEA:Ensembl
Biological Process endothelial cell morphogenesisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process growth plate cartilage axis specificationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of calcium ion transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of cell migrationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of endothelial cell migrationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of renal phosphate excretionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process ossificationIEA:Ensembl
Biological Process positive regulation of calcium ion importManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of anion transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of cardiac muscle cell contractionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process response to vitamin DIEA:Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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