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Mouse Anti-STON1 Recombinant Antibody (CBXS-4112) (CBMAB-S1368-CQ)

This product is a mouse antibody that recognizes STON1. The antibody CBXS-4112 can be used for immunoassay techniques such as: ELISA, ICC, IF.
See all STON1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4112
Antibody Isotype
IgG2a, κ
Application
ELISA, ICC, IF

Basic Information

Immunogen
STON1 (NP_006864, 529 a.a.-620 a.a) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Stonin 1
Introduction
Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Read-through transcription of this gene into the neighboring downstream gene, which encodes TFIIA-alpha/beta-like factor, generates a transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
11037
UniProt ID
Q9Y6Q2
Alternative Names
SALF; SBLF; STN1; STNB1
Function
May be involved in the endocytic machinery.
Biological Process
Biological Process focal adhesion assemblyIEA:Ensembl
Biological Process focal adhesion disassemblyIEA:Ensembl
Biological Process platelet-derived growth factor receptor signaling pathwayIEA:Ensembl
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process ruffle assemblyIEA:Ensembl
Biological Process substrate-dependent cell migrationIEA:Ensembl
Biological Process synaptic vesicle endocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Membrane
Some fraction is membrane-associated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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