Mouse Anti-STRA8 Recombinant Antibody (CBXS-5716) (CBMAB-S0583-CQ)

Name: Mouse Anti-STRA8 Recombinant Antibody (CBXS-5716)
SKU: CBMAB-S0583-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-5716

Application

Immunogen

KLH conjugated synthetic peptide between 31-59 amino acids from human STRA8

Specificity

Human, Mouse

Antibody Isotype

IgM

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

0.09% sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Stimulated By Retinoic Acid 8

Introduction

This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans.

Entrez Gene ID

Human	346673
Mouse	20899

UniProt ID

Human	Q7Z7C7
Mouse	P70278

Alternative Names

Stimulated By Retinoic Acid 8

Function

Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis.

Biological Process

Biological Process activation of meiosisISS:UniProtKB
Biological Process cellular response to retinoic acidISS:UniProtKB
Biological Process DNA replicationIEA:UniProtKB-KW
Biological Process meiotic cell cycleISS:UniProtKB
Biological Process oogenesisISS:UniProtKB
Biological Process regulation of transcription by RNA polymerase IIISS:UniProtKB
Biological Process spermatogenesisISS:UniProtKB

Cellular Location

Cytoplasm
Nucleus
Shuttles between nucleus and cytoplasm. Nuclear export is XPO1-dependent.

PTM

Phosphorylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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