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Mouse Anti-STRA8 Recombinant Antibody (CBXS-5716) (CBMAB-S0583-CQ)

This product is a mouse antibody that recognizes STRA8. The antibody CBXS-5716 can be used for immunoassay techniques such as: WB.
See all STRA8 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CBXS-5716
Antibody Isotype
IgM
Application
WB

Basic Information

Immunogen
KLH conjugated synthetic peptide between 31-59 amino acids from human STRA8
Specificity
Human, Mouse
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
0.09% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Stimulated By Retinoic Acid 8
Introduction
This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans.
Entrez Gene ID
Human346673
Mouse20899
UniProt ID
HumanQ7Z7C7
MouseP70278
Alternative Names
Stimulated By Retinoic Acid 8
Function
Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis.
Biological Process
Biological Process activation of meiosisISS:UniProtKB
Biological Process cellular response to retinoic acidISS:UniProtKB
Biological Process DNA replicationIEA:UniProtKB-KW
Biological Process meiotic cell cycleISS:UniProtKB
Biological Process oogenesisISS:UniProtKB
Biological Process regulation of transcription by RNA polymerase IIISS:UniProtKB
Biological Process spermatogenesisISS:UniProtKB
Cellular Location
Cytoplasm
Nucleus
Shuttles between nucleus and cytoplasm. Nuclear export is XPO1-dependent.
PTM
Phosphorylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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