Mouse Anti-Stxbp5 Recombinant Antibody (CBYJT-1691) (CBMAB-T0741-YJ)

Name: Mouse Anti-Stxbp5 Recombinant Antibody (CBYJT-1691)
SKU: CBMAB-T0741-YJ
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBYJT-1691

Application

WB, Bioimaging, IF

Immunogen

Rat Tomosyn aa. 910-1105

Specificity

Rat, Human, Mouse

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 910-1105

More Infomation

Target

Full Name

Syntaxin Binding Protein 5

Introduction

Stxbp5 is a syntaxin-binding protein implicated in the formation of complexes involved in neurotransmitter release.

Entrez Gene ID

Human	134957
Mouse	78808
Rat	81022

UniProt ID

Human	Q5T5C0
Mouse	Q8K400
Rat	Q9WU70

Alternative Names

syntaxin-binding protein 5; lethal(2) giant larvae protein homolog 3; tomosyn; tomosyn-1

Function

Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity).

Biological Process

Biological Process exocytosisIEA:UniProtKB-KW
Biological Process positive regulation of exocytosisISS:BHF-UCL
Biological Process protein transportIEA:UniProtKB-KW
Biological Process regulation of exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of protein secretionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of synaptic vesicle exocytosisIEA:Ensembl
Biological Process regulation of synaptic vesicle primingIEA:Ensembl

Cellular Location

Cytoplasm
Cell membrane
Cytoplasmic vesicle membrane
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle
Synapse
Cytoplasmic, and associated with vesicular membranes and the plasma membrane. Detected at synapses and on synaptic vesicles (By similarity).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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