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Mouse Anti-Stxbp5 Recombinant Antibody (CBYJT-1691) (CBMAB-T0741-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Stxbp5 (Syntaxin Binding Protein 5). The antibody can be used for immunoassay techniques, such as WB, Bioimaging, IF.
See all Stxbp5 antibodies

Summary

Host Animal
Mouse
Specificity
Rat, Human, Mouse
Clone
CBYJT-1691
Antibody Isotype
IgG1
Application
WB, Bioimaging, IF

Basic Information

Immunogen
Rat Tomosyn aa. 910-1105
Specificity
Rat, Human, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 910-1105

Target

Full Name
Syntaxin Binding Protein 5
Introduction
Stxbp5 is a syntaxin-binding protein implicated in the formation of complexes involved in neurotransmitter release.
Entrez Gene ID
Human134957
Mouse78808
Rat81022
UniProt ID
HumanQ5T5C0
MouseQ8K400
RatQ9WU70
Alternative Names
syntaxin-binding protein 5; lethal(2) giant larvae protein homolog 3; tomosyn; tomosyn-1
Function
Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity).
Biological Process
Biological Process exocytosisIEA:UniProtKB-KW
Biological Process positive regulation of exocytosisISS:BHF-UCL
Biological Process protein transportIEA:UniProtKB-KW
Biological Process regulation of exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of protein secretionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of synaptic vesicle exocytosisIEA:Ensembl
Biological Process regulation of synaptic vesicle primingIEA:Ensembl
Cellular Location
Cytoplasm
Cell membrane
Cytoplasmic vesicle membrane
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle
Synapse
Cytoplasmic, and associated with vesicular membranes and the plasma membrane. Detected at synapses and on synaptic vesicles (By similarity).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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