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Rabbit Anti-SUN3 Recombinant Antibody (CBXS-1336) (CBMAB-S4194-CQ)

This product is a rabbit antibody that recognizes SUN3. The antibody CBXS-1336 can be used for immunoassay techniques such as: WB, FC, IF.
See all SUN3 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBXS-1336
Antibody Isotype
IgG
Application
WB, FC, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
0.578 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Sad1 and UNC84 domain containing 3
Entrez Gene ID
UniProt ID
Alternative Names
SUNC1
Function
As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenesis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
Biological Process
Nuclear envelope organization
Cellular Location
Membrane
Nucleus envelope
Nucleus inner membrane
Topology
Nuclear: 1-47
Helical: 48-64
Perinuclear space: 65-357
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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