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Mouse Anti-TADA2B Recombinant Antibody (CBYJT-1812) (CBMAB-T0874-YJ)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYJT-1812
Antibody Isotype
IgG2a, κ
Application
ELISA, IHC, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa2-111 from MGC21874 (XP_291105) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 2-111

Target

Full Name
TADA2B
Introduction
TADA2B plays a role as a transcriptional adaptor protein that potentiates transcription through coordination of histone acetyltransferase (HAT) activity and by linking activation factors to basal transcriptional machinery (Barlev et al., 2003 [PubMed 12972612]).
Entrez Gene ID
Human93624
Mouse231151
Rat289717
UniProt ID
HumanQ86TJ2
MouseD3Z4Z0
RatF7EYV9
Alternative Names
Transcriptional Adaptor 2B; ADA2-Like Protein Beta; ADA2-Beta; ADA2B; Transcriptional Adaptor 2 (ADA2 Homolog, Yeast)-Beta; Transcriptional Adapter 2-Beta; ADA2(Beta)
Function
Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2.
Biological Process
Biological Process chromatin remodelingIBA:GO_Central1 Publication
Biological Process histone H3 acetylationIC:ComplexPortal1 Publication
Biological Process monoubiquitinated histone deubiquitinationIDA:ComplexPortal1 Publication
Biological Process monoubiquitinated histone H2A deubiquitinationIDA:ComplexPortal1 Publication
Biological Process positive regulation of DNA-templated transcriptionIC:ComplexPortal1 Publication
Biological Process positive regulation of histone acetylationIBA:GO_Central1 Publication
Biological Process regulation of DNA repairIC:ComplexPortal1 Publication
Biological Process regulation of RNA splicingIC:ComplexPortal1 Publication
Biological Process regulation of transcription by RNA polymerase IIIBA:GO_Central1 Publication
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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