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Recombinant Mouse Anti-TAF7L Recombinant Antibody (2D5) (CBMAB-XB1100-YC)


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Summary

Host Animal
Mouse
Specificity
Mouse
Clone
2D5
Antibody Isotype
IgG1, κ
Application
ELISA, IHC, WB

Basic Information

Immunogen
Synthetic peptide TKKLPDVKQVDEINFSEYTQ corresponding to amino acids 154-173 of mouse TAF7L
Specificity
Mouse
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
Introduction
TAF7L is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID.
Entrez Gene ID
54457
UniProt ID
Q5H9L4
Alternative Names
TATA-Box Binding Protein Associated Factor 7 Like; Cancer/Testis Antigen 40; TAF7-Like RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 50kDa; Transcription Initiation Factor TFIID 50 KDa Subunit; RNA Polymerase II TBP-Associated Factor Subunit Q; TATA Box-Binding Protein-Associated Factor 50 KDa;
Function
Probably functions as a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis (By similarity).
Biological Process
Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process RNA polymerase II preinitiation complex assemblyIBA:GO_Central1 Publication
Biological Process spermatogenesisIEA:UniProtKB-KW
Cellular Location
Nucleus
Cytoplasm
Cytoplasmic in spermatogonia and early spermatocytes (preleptotene, leptotene, and zygotene); translocates into the nuclei of pachytene spermatocytes and round spermatids.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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