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Mouse Anti-TAL2 Recombinant Antibody (CBYJT-1929) (CBMAB-T1013-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TAL2 (TAL BHLH Transcription Factor 2). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TAL2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-1929
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa29-109 from human TAL2 (NP_005412) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 29-109

Target

Full Name
T-cell acute lymphocytic leukemia 2
Introduction
TAL2 is a helix-loop-helix protein. Translocations between TAL2 on chromosome 9 and the T-cell receptor beta-chain locus on chromosome 7 have been associated with activation of the T-cell acute lymphocytic leukemia 2 gene and T-cell acute lymphoblastic leukemia.
Entrez Gene ID
6887
UniProt ID
Q16559
Alternative Names
TAL BHLH Transcription Factor 2; Class A Basic Helix-Loop-Helix Protein 19; T-Cell Acute Lymphocytic Leukemia 2; TAL-2; T-Cell Acute Lymphocytic Leukemia Protein 2; BHLHA19
Biological Process
Biological Process midbrain developmentIEA:Ensembl
Biological Process multicellular organism growthIEA:Ensembl
Biological Process post-embryonic developmentIEA:Ensembl
Biological Process regulation of transcription by RNA polymerase IIIBA:GO_Central1 Publication
Biological Process thalamus developmentIEA:Ensembl
Cellular Location
Chromatin
Involvement in disease
A chromosomal aberration involving TAL2 may be a cause of some T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(7;9)(q34;q32) with TCRB.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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