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Mouse Anti-TALA Recombinant Antibody (227-341-4) (CBMAB-0096-CN)

This product is a mouse antibody that recognizes TALA of Dictyostelium discoideum. The antibody 227-341-4 can be used for immunoassay techniques such as: WB.
See all TALA antibodies

Summary

Host Animal
Mouse
Specificity
D. discoideum, Dictyostelium
Clone
227-341-4
Antibody Isotype
IgG1, κ
Application
WB

Basic Information

Immunogen
Dictyostelium talinA
Specificity
D. discoideum, Dictyostelium
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Hypothetical protein
Introduction
The AX4 talin gene has a confirmed stop codon (R. Kay, private communication) that terminates the protein after residue 1,279; immunohistochemistry shows the presence of a very faint truncated talin (A. Mueller-Taubenberger, private communication). AX2 talin is the full length homolog of mammalian talin and other proteins of the band 4.1 superfamily; all functional data is derived from AX2; involved in cell-substrate adhesion and cytokinesis.
Entrez Gene ID
8627718
UniProt ID
P0CE94
Alternative Names
talin A; filopodin
Function
Actin-binding protein that may be involved in the control of cell motility and chemotaxis.
Biological Process
Biological Process actomyosin contractile ring contractionIMP:dictyBase1 Publication
Biological Process cell morphogenesisIMP:dictyBase1 Publication
Biological Process cell-cell adhesionIMP:dictyBase1 Publication
Biological Process cell-substrate adhesionIMP:dictyBase2 Publications
Biological Process cleavage furrow ingressionIMP:dictyBase1 Publication
Biological Process mitotic cytokinesisIMP:dictyBase2 Publications
Biological Process phagocytosisIMP:dictyBase2 Publications
Biological Process sorocarp developmentIGI:dictyBase1 Publication
Biological Process uropod retractionIMP:dictyBase1 Publication
Cellular Location
Cytoplasm, cytoskeleton
Cytoplasm, cell cortex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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