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Mouse Anti-TBC1D3F Recombinant Antibody (C-8) (CBMAB-P3701-YC)

Provided herein is a Mouse monoclonal antibody against Human TBC1 Domain Family Member 3F. The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all TBC1D3F antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
C-8
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TBC1 Domain Family Member 3F
Introduction
TBC1D3F (TBC1 Domain Family Member 3F) is a protein coding gene. Gene Ontology annotations related to this gene include GTPase activator activity. An important paralog of the gene is TBC1D3.
Entrez Gene ID
84218
UniProt ID
A6NER0
Alternative Names
TBC1D3A; TBC1D3D; TBC1D3F; PRC17; TBC1D3I; TBC1D3; TBC1D3L
Function
Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).
Biological Process
Activation of GTPase activity
Cellular Location
Cell membrane
Associated with lipid rafts.
PTM
Ubiquitinated by a CUL7-based E3 ligase, which leads to proteasomal degradation.
Palmitoylation is required for membrane localization and protects TBC1D3 from ubiquitination.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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