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Mouse Anti-TCEA3 Recombinant Antibody (CBYJT-2223) (CBMAB-T1330-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TCEA3 (Transcription Elongation Factor A3). The antibody can be used for immunoassay techniques, such as ICC, IF, IP, WB.
See all TCEA3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2223
Antibody Isotype
IgG2a, κ
Application
ICC, IF, IP, WB

Basic Information

Immunogen
TCEA3 (AAH41613, 1 a.a. ~ 348 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-348

Target

Full Name
TCEA3 Gene(Protein Coding) Transcription Elongation Factor A3
Introduction
TCEA3 (Transcription Elongation Factor A3) is a Protein Coding gene. Diseases related to TCEA3 include Cockayne Syndrome. Among its related pathways are RNA Polymerase II Transcription Initiation And Promoter Clearance. Gene Ontology (GO) annotations related to TCEA3 include nucleic acid binding. An important paralog of TCEA3 is TCEA1.
Entrez Gene ID
6920
UniProt ID
O75764
Alternative Names
Transcription Elongation Factor A3; Transcription Elongation Factor S-II Protein 3; Transcription Elongation Factor A (SII), 3; Transcription Elongation Factor TFIIS.H; Transcription Elongation Factor A Protein 3; Rhabdomyosarcoma Antigen MU-RMS-40.22; TFIIS.H; TFIISH; TFIIS
Function
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
Biological Process
Biological Process DNA-templated transcriptionIBA:GO_Central1 Publication
Biological Process transcription elongation by RNA polymerase II promoterIEA:InterPro
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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