Mouse Anti-TCF12 Recombinant Antibody (CBYJT-2248) (CBMAB-T1357-YJ)

Name: Mouse Anti-TCF12 Recombinant Antibody (CBYJT-2248)
SKU: CBMAB-T1357-YJ
Rating: 5 (1 reviews)

See all TCF12 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYJT-2248

Application

ELISA, IF, IHC-P, WB

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 364-454

More Infomation

Target

Full Name

TCF12 Gene(Protein Coding) Transcription Factor 12

Introduction

TCF12 is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins.

Entrez Gene ID

6938

UniProt ID

Q99081

Alternative Names

Transcription Factor 12; Class B Basic Helix-Loop-Helix Protein 20; Helix-Loop-Helix Transcription Factor 4; Transcription Factor HTF-4; DNA-Binding Protein HTF4; E-Box-Binding Protein; BHLHb20

Function

Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').

Biological Process

Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process immune responseTAS:ProtInc1 Publication
Biological Process muscle organ developmentTAS:ProtInc1 Publication
Biological Process nervous system developmentIEA:UniProtKB-KW
Biological Process positive regulation of gene expressionIEA:Ensembl
Biological Process positive regulation of neuron differentiationIEA:Ensembl
Biological Process positive regulation of transcription by RNA polymerase IIIDA:NTNU_SB1 Publication
Biological Process regulation of transcription by RNA polymerase IIIBA:GO_Central1 Publication

Cellular Location

Nucleus

Involvement in disease

Craniosynostosis 3 (CRS3):
A primary abnormality of skull growth involving premature fusion of one or more cranial sutures. The growth velocity of the skull often cannot match that of the developing brain resulting in an abnormal head shape and, in some cases, increased intracranial pressure, which must be treated promptly to avoid permanent neurodevelopmental disability.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-TCF12 Recombinant Antibody (CBYJT-2248)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-TCF12 Recombinant Antibody (CBYJT-2243) (CAT#: CBMAB-T1352-YJ)

Rabbit Anti-TCF12 Recombinant Antibody (CBYJT-2249) (CAT#: CBMAB-T1358-YJ)

Mouse Anti-TCF12 Recombinant Antibody (CBFYH-2788) (CAT#: CBMAB-H3857-FY)

Mouse Anti-TCF12 Recombinant Antibody (CBFYH-2786) (CAT#: CBMAB-H3855-FY)

Mouse Anti-TCF12 Recombinant Antibody (CBYJT-2247) (CAT#: CBMAB-T1356-YJ)

Mouse Anti-TCF12 Recombinant Antibody (2E9) (CAT#: CBMAB-A8943-LY)

Mouse Anti-TCF12 Recombinant Antibody (CBYJT-2246) (CAT#: CBMAB-T1355-YJ)

Mouse Anti-TCF12 Recombinant Antibody (CBYJT-2245) (CAT#: CBMAB-T1354-YJ)

Mouse Anti-TCF12 Recombinant Antibody (CBYJT-2244) (CAT#: CBMAB-T1353-YJ)

Mouse Anti-TCF12 Recombinant Antibody (CBFYH-2787) (CAT#: CBMAB-H3856-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry