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Mouse Anti-TEP1 Recombinant Antibody (CBYJT-2520) (CBMAB-T1673-YJ)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2520
Antibody Isotype
IgG
Application
WB, ICC, IHC-P, IHC-Fr, ELISA

Basic Information

Immunogen
Telomerase Associated Protein 1
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4, 50% Glycerol
Preservative
0.02% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Telomerase Associated Protein 1
Introduction
TEP1 is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans.
Entrez Gene ID
UniProt ID
Alternative Names
Telomerase Associated Protein 1; TROVE Domain Family, Member 1; P80 Telomerase Homolog; Telomerase Protein 1; P240; TLP1
Function
Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini (PubMed:19179534).
Also a component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport (By similarity).
Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC (By similarity).
Biological Process
Telomere maintenance via recombination
Cellular Location
Nucleus
Chromosome, telomere
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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