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Mouse Anti-THAP12 Recombinant Antibody (CBYJT-2907) (CBMAB-T2142-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to THAP12 (THAP Domain Containing 12). The antibody can be used for immunoassay techniques, such as ELISA.
See all THAP12 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2907
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Immunogen
PRKRIR (AAH21992, 1 a.a. ~ 150 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-150

Target

Full Name
THAP12
Introduction
THAP12 (THAP Domain Containing 12) is an upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). It may block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth.
Entrez Gene ID
5612
UniProt ID
O43422
Alternative Names
THAP Domain Containing 12; Death-Associated Protein 4; Protein-Kinase, Interferon-Inducible Double Stranded RNA Dependent Inhibitor, Repressor Of (P58 Repressor); 58 KDa Interferon-Induced Protein Kinase-Interacting Protein; 52 KDa Repressor Of The Inhibitor Of The Protein Kinase; THAP Domain-Containing Protein 12; THAP Domain-Containing Protein 0; P58IPK-Interacting Protein
Function
Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth.
Biological Process
Biological Process negative regulation of cell population proliferationSource:ProtInc1 Publication
Biological Process signal transductionSource:ProtInc1 Publication
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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