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Mouse Anti-TIAF1 Recombinant Antibody (CBYJT-3105) (CBMAB-T2373-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TIAF1 (TGFB1-Induced Anti-Apoptotic Factor 1). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TIAF1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3105
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
TIAF1 (NP_004731.2, 1 a.a. ~ 115 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: MSSPSSPFRE QSFLCAAGDA GEESRVQVLK NEVRRGSPVL LGWVEQAYAD KCVCGPSAPP APTPPSLSQR VMCNDLFKVN PFQLQQFRAD PSTASLLLCP GGLDHKLNLR GKAWG
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-115

Target

Full Name
TGFB1-induced anti-apoptotic factor 1
Introduction
TIAF1 (TGFB1-Induced Anti-apoptotic Factor 1) inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. It is involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation.
Entrez Gene ID
9220
UniProt ID
O95411
Alternative Names
TGFB1-Induced Anti-Apoptotic Factor 1; 12 KDa TGF-Beta-1-Induced Antiapoptotic Factor; TGF-Beta-1-Induced Antiapoptotic Factor 1; Molecule Associated With Jak-3 N-Terminal; SPR210; MAJN
Function
Isoform TIAF1
Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation.
Biological Process
Biological Process apoptotic processSource:UniProtKB-KW
Biological Process I-kappaB kinase/NF-kappaB signalingSource:UniProtKB1 Publication
Biological Process negative regulation of apoptotic processSource:UniProtKB1 Publication
Cellular Location
Isoform TIAF1
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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