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Mouse Anti-TIMM10B Recombinant Antibody (CBYJT-3166) (CBMAB-T2440-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3166
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
FXC1 (NP_036324.1, 11 a.a. ~ 103 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 11-103

Target

Full Name
Translocase Of Inner Mitochondrial Membrane 10B
Introduction
TIMM10B, or FXC1, belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.
Entrez Gene ID
26515
UniProt ID
Q9Y5J6
Alternative Names
Translocase Of Inner Mitochondrial Membrane 10B; Mitochondrial Import Inner Membrane Translocase Subunit Tim9 B; Fracture Callus Protein 1; TIM10B; Tim9b; FXC1; Translocase Of Inner Mitochondrial Membrane 10 Homolog B (Yeast)
Function
Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space.
Biological Process
Biological Process cell-matrix adhesionSource:ProtInc1 Publication
Biological Process protein insertion into mitochondrial inner membraneSource:FlyBase
Cellular Location
Mitochondrion inner membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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