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Mouse Anti-TMEM17 Recombinant Antibody (CBYJT-3492) (CBMAB-T2817-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TMEM17 (Transmembrane Protein 17). The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all TMEM17 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat, Mouse
Clone
CBYJT-3492
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Specific for an epitope mapping between amino acids 1-17 at the N-terminus of TMEM17 of human origin
Specificity
Human, Rat, Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-17

Target

Full Name
Transmembrane Protein 17
Introduction
TMEM17 (Transmembrane Protein 17) is a Protein Coding gene. Diseases associated with TMEM17 include Orofaciodigital Syndrome Vi and Meckel Syndrome, Type 1.
Entrez Gene ID
Human200728
Mouse103765
Rat360985
UniProt ID
HumanQ86X19
MouseQ8K0U3
RatQ5HZE5
Alternative Names
Transmembrane Protein 17
Function
Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
Biological Process
Biological Process cilium assemblySource:UniProtKB
Biological Process non-motile cilium assemblySource:WormBase1 Publication
Biological Process smoothened signaling pathwaySource:UniProtKB
Cellular Location
Cell projection, cilium membrane
Localizes to the transition zone of primary cilia.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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