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Mouse Anti-TMSB4Y Recombinant Antibody (6G4) (CBMAB-A9229-LY)

The product is antibody recognizes TMSB4Y. The antibody 6G4 immunoassay techniques such as: WB, ELISA.
See all TMSB4Y antibodies
Published Data
Fig. 1 Western blotting using an anti-TMSB4Y antibody and GAPDH antibody as loading control
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Fig. 2 Immunohistochemistry labeling of FFPE cell pellets using an anti-TMSB4Y antibody and counterstaining. Original magnification: 20X.
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Fig. 3 Cell lysates were also used for immunoprecipitation (IP) experiments using a TMSB4Y antibody on Dox-induced lysates from EV and TmY1. The TMSB4Y antibody was used for IP, and then total lysate (1), supernatant after IP (2) or the IP fraction (3) was stained via western blot using anti-TMSB4Y and anti-β-actin antibodies.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
6G4
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
TMSB4Y (NP_004193.1, 1 a.a. ~ 44 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
thymosin beta 4, Y-linked
Introduction
This gene lies within the male specific region of chromosome Y. Its homolog on chromosome X escapes X inactivation and encodes an actin sequestering protein. [provided by RefSeq]
Entrez Gene ID
9087
UniProt ID
O14604
Alternative Names
MGC26307; TB4Y
Function
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
Biological Process
Biological Process actin filament organizationSource:InterPro
Biological Process regulation of actin polymerization or depolymerizationSource:ProtInc1 Publication
Biological Process regulation of cell migrationSource:GO_Central1 Publication
Biological Process sequestering of actin monomersSource:GO_Central1 Publication
Cellular Location
Cytoplasm, cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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