Sign in or Register   Sign in or Register
  |  

Mouse Anti-TRAPPC2 Recombinant Antibody (CBYJT-4557) (CBMAB-T4070-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TRAPPC2 (Trafficking Protein Particle Complex 2). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TRAPPC2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-4557
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
Full length recombinant corresponding to aa1-141 from human TRAPPC2 (AAH16915) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-141

Target

Full Name
trafficking protein particle complex 2
Introduction
TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene can cause spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y.
Entrez Gene ID
6399
UniProt ID
P0DI81
Alternative Names
Trafficking Protein Particle Complex 2; Sedlin; SEDL; Trafficking Protein Particle Complex Subunit 2; Spondyloepiphyseal Dysplasia, Late; TRAPPC2P1
Function
Prevents transcriptional repression and induction of cell death by ENO1 (By similarity).
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Biological Process
Biological Process COPII vesicle coating Source:ComplexPortal1 Publication
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transport Source:GO_Central1 Publication
Biological Process skeletal system development Source:UniProtKB1 Publication
Biological Process vesicle coating Source:ComplexPortal1 Publication
Biological Process vesicle tethering Source:ComplexPortal1 Publication
Cellular Location
Cytoplasm, perinuclear region
Endoplasmic reticulum-Golgi intermediate compartment
Nucleus
Cytoplasm
Localized in perinuclear granular structures.
Involvement in disease
Spondyloepiphyseal dysplasia tarda (SEDT):
X-linked recessive disorder of endochondral bone formation.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-TRAPPC2 Recombinant Antibody (CBYJT-4557)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare