Mouse Anti-TRDMT1 Recombinant Antibody (CBYJT-4588) (CBMAB-T4107-YJ)

Name: Mouse Anti-TRDMT1 Recombinant Antibody (CBYJT-4588)
SKU: CBMAB-T4107-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYJT-4588

Application

S-ELISA, ELISA, WB, IF

Immunogen

DNMT2 (AAH47733, 1 a.a. ~ 391 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa

Specificity

Human

Antibody Isotype

IgG1, λ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1-391

More Infomation

Target

Full Name

TRDMT1 Gene(Protein Coding) TRNA Aspartic Acid Methyltransferase 1

Introduction

TRDMT1 is a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. TRDMT1 also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, TRDMT1 is distinct and highly conserved in its function among taxa.

Entrez Gene ID

1787

UniProt ID

O14717

Alternative Names

TRNA Aspartic Acid Methyltransferase 1; DNA (Cytosine-5)-Methyltransferase-Like Protein 2; TRNA (Cytosine(38)-C(5))-Methyltransferase; DNA MTase Homolog HsaIIP; PUMET; DNMT2; DNA (Cytosine-5-)-Methyltransferase 2; TRNA (Cytosine-5-)-Methyltransferase; DNA Methyltransferase Homolog HsaIIP; DNA Cytosine-5 Methyltransferase 2

Function

Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).

Biological Process

Biological Process response to amphetamine Source:Ensembl
Biological Process tRNA C5-cytosine methylation Source:GO_Central1 Publication
Biological Process tRNA methylation Source:MGI1 Publication
Biological Process tRNA modification Source:Reactome
Biological Process tRNA stabilization Source:UniProtKB

Cellular Location

Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

TRDMT1 Matched Antibody Pair (1268) (CAT#: APMAB-1268LY)

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Mouse Anti-TRDMT1 Recombinant Antibody (CBYJT-4586) (CAT#: CBMAB-T4105-YJ)

TRDMT1 Matched Antibody Pair (1268) (CAT#: APMAB-1268LY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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