Rat Anti-Trem3 Recombinant Antibody (CBYJT-4617) (CBMAB-T4146-YJ)

Name: Rat Anti-Trem3 Recombinant Antibody (CBYJT-4617)
SKU: CBMAB-T4146-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Rat

Clone

CBYJT-4617

Application

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse TREM-3 Met1-Pro135 (predicted)

Specificity

Mouse

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, 5% Trehalose

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1-135

More Infomation

Target

Full Name

Triggering Receptor Expressed On Myeloid Cells 3

Introduction

Trem3 is part of the immunoglobulin and lectin-like superfamily and is thought to play a role as part of the innate immune system. Trem3 forms part of a cluster of genes on mouse chromosome 17 thought to be involved in innate immunity. It has been reported to associate with the adaptor protein Dap-12 to form a receptor signaling complex that activates myeloid cells.

Entrez Gene ID

58218

UniProt ID

Q9JKE1

Alternative Names

TREM-3; BB134760

Function

Forms a receptor signaling complex with TYROBP/DAP12 which mediates activation of macrophages as part of the innate immune response.

Biological Process

Biological Process cell migration Source:MGI1 Publication
Biological Process neutrophil chemotaxis Source:MGI1 Publication
Biological Process neutrophil extravasation Source:MGI1 Publication
Biological Process neutrophil-mediated killing of gram-negative bacterium Source:MGI1 Publication
Biological Process positive regulation of innate immune response Source:UniProtKB1 Publication

Cellular Location

Cell membrane

Topology

Extracellular: 20-138
Helical: 139-159
Cytoplasmic: 160-183

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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