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Mouse Anti-TRIM27 Monoclonal Antibody (1B3) (CBMAB-0271-LY)

This product is mouse monoclonal antibody recognizes TRIM27 of human. The antibody 1B3 immunoassay techniques such as: IP, MA.
Host Species
Mouse
Application
IP, MA
Immunogen
Recombinant peptide (Full Length)
Antibody Isotype
IgG2c
Specificity
Human
Clone
1B3
Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity; mediates the formation of 'Lys-48'-linked polyubiquitin chains; the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASHC1, leading to promote endosomal F-actin assembly.
Alternative Name
RFP; RNF76
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0271-LY
Conjugates
Size
Price $
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Second antibody and isotype control