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Mouse Anti-TRIM31 Recombinant Antibody (2G11) (CBMAB-A9512-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2G11
Antibody Isotype
IgG2a, κ
Application
IF, ELISA

Basic Information

Immunogen
TRIM31 (NP_008959, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
tripartite motif-containing 31
Introduction
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to both the cytoplasm and the nucleus. Its function has not been identified. [provided by RefSeq]
Entrez Gene ID
11074
UniProt ID
Q9BZY9
Alternative Names
C6orf13; HCG1; HCGI; RNF
Function
Regulator of Src-induced anchorage independent cell growth (By similarity).
May have E3 ubiquitin-protein ligase activity.
Biological Process
Biological Process innate immune response Source:UniProtKB1 Publication
Biological Process negative regulation of viral entry into host cell Source:UniProtKB1 Publication
Biological Process negative regulation of viral transcription Source:UniProtKB1 Publication
Biological Process positive regulation of DNA-binding transcription factor activity Source:UniProtKB1 Publication
Biological Process protein ubiquitination Source:GO_Central1 Publication
Biological Process regulation of gene expression Source:GO_Central1 Publication
Biological Process viral release from host cell Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
Mitochondrion
Predominantly expressed in the cytoplasm but a fraction is associated with the mitochondria.
PTM
Auto-ubiquitinated (in vitro).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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